Cinirant Tablet: Uses, Dosage, Side Effects, And Warnings

Cinirant Tablet is a prescription medication that contains Cinitapride, a gastroprokinetic agent used to treat conditions like acid reflux, indigestion, and gastroparesis. It works by enhancing the movement of food through the digestive tract, reducing discomfort caused by delayed stomach emptying and reflux.

Introduction

Cinirant belongs to a class of medications called benzamides. Its active ingredient, Cinitapride, stimulates certain receptors in the gastrointestinal (GI) tract, promoting the release of neurotransmitters like acetylcholine. This activity improves gut motility, helping food move efficiently from the stomach to the intestines.

Ingredients

It contains Cinitapride as an active ingredient.

Drug Class

• Benzamides

How Cinirant Tablet Works

Cinirant works on dopamine D2 receptors and serotonin 5-HT4 receptors in the gut. By enhancing the release of acetylcholine, it promotes muscular contractions that move food forward, while also preventing the backward flow of stomach acid.

Cinirant Tablet Uses

Cinirant is primarily used to treat:

• Gastroesophageal Reflux Disease (GERD)
  Relieves heartburn and acid regurgitation by tightening the lower esophageal sphincter.

• Functional Dyspepsia (Indigestion)
  Alleviates bloating, early satiety, and discomfort by improving stomach contractions.

• Gastroparesis
  Useful in diabetic or idiopathic gastroparesis where the stomach empties too slowly.

• Nausea and Vomiting
  Especially beneficial when caused by slowed gut movement.

Cinirant Tablet Dosage

Always follow your doctor’s advice. Below is a general dosage table:

How to Use Cinirant Tablet

• Swallow the tablet whole with water.

• Take before meals (usually 2–3 times daily).

• Follow the full treatment duration (typically 4–12 weeks).

• Do not skip or double your dose.

If you miss a dose, take it as soon as you remember. If it’s close to the next dose, skip it—don’t double up.

Who Should Not Take Cinirant?

Avoid Cinirant if you:

• Are allergic to Cinitapride or any ingredients in the tablet

• Have GI bleeding, obstruction, or perforation

• Are pregnant or breastfeeding (unless prescribed by your doctor)

• Have serious heart rhythm disorders

Side Effects of Cinirant Tablet

Most side effects are mild and go away on their own. However, consult your doctor if they persist.

Common Side Effects:

• Headache

• Dizziness

• Nausea or vomiting

• Diarrhea

• Drowsiness

• Abdominal discomfort

Rare but Serious:

• Irregular heartbeat

• Muscle stiffness or tremors

• Allergic reactions (rash, swelling, difficulty breathing)

Warnings and Precautions

Before starting Cinirant tablet, it’s crucial to be aware of specific warnings and safety precautions to avoid complications and ensure optimal treatment outcomes.

General Warnings

• Not for Self-Medication
  Always use Cinirant under medical supervision. Misuse or overuse can lead to serious side effects.

• Short-Term Use Recommended
  Cinirant is typically prescribed for a short duration (4–12 weeks). Long-term use should only be done under regular medical monitoring.

• Avoid Abrupt Discontinuation
  Do not stop the medication suddenly without your doctor’s advice, especially if you’re on a high dose or taking it long-term.

Cardiovascular Risk

• Heart Rhythm Disturbances
  Cinirant may affect cardiac conduction in rare cases. Use cautiously if you have:

  • QT prolongation

  • History of arrhythmias

  • Congenital heart conditions

Nervous System Effects

• Drowsiness & Dizziness
  Cinirant may cause sleepiness, especially when combined with alcohol or other sedatives. Avoid driving or operating heavy machinery until you know how it affects you.

• Extrapyramidal Symptoms (rare)
  Muscle stiffness, tremors, or restlessness may occur—more common in elderly or those on higher doses.

Use in Special Populations

• Pregnancy
  Not recommended during pregnancy unless clearly needed. Consult your doctor to weigh the risks and benefits.

• Breastfeeding
  Safety during breastfeeding is not fully established. Avoid unless your doctor advises otherwise.

• Children & Elderly
  Use in children should be closely monitored. Elderly patients may be more sensitive to its side effects, particularly drowsiness or confusion.

Liver & Kidney Function

• Liver Disease
  Use with caution in patients with liver impairment. Dose adjustments may be required.

• Kidney Impairment
  Although not primarily excreted via the kidneys, caution is advised in those with chronic kidney disease (CKD).

When Not to Use Cinirant Tablet

Do not use Cinirant if you:

• Are allergic to Cinitapride or any of its ingredients

• Have a history of gastrointestinal bleeding, perforation, or obstruction

• Are currently taking medications that prolong the QT interval

• Have severe heart conditions, especially uncontrolled arrhythmias

Always inform your doctor about your medical history before starting this medication.

Alternatives to Cinirant Tablet

Here are some other medications that may be used for similar conditions:

Storage & Disposal

• Store at room temperature (15–25°C)

• Keep away from moisture and direct sunlight

• Keep out of reach of children and pets

• Don’t use it after expiration.

Disclaimer

This article is for information purposes only Please don’t take it as medical advice. please consult a doctor for prescription.