Introduction
Froben Tablet is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, fever, and inflammation. It belongs to the propionic acid class of NSAIDs, similar to ibuprofen. Froben is commonly prescribed for arthritis and other musculoskeletal disorders.
2. Mechanism
Froben works by blocking COX-1 and COX-2 enzymes, which are responsible for converting arachidonic acid into prostaglandins—chemicals that trigger pain, fever, and inflammation. By reducing prostaglandin production, Froben relieves pain and swelling. However, since it also affects protective prostaglandins, it can cause stomach and kidney side effects.
3. Uses Of Froben Tablet
Froben is indicated for:
- Rheumatoid arthritis and osteoarthritis
- Ankylosing spondylitis
- Musculoskeletal pain (e.g., tendinitis, bursitis, frozen shoulder, back pain)
- Mild-to-moderate acute pain (e.g., dental pain, post-surgery pain)
- Primary dysmenorrhea (menstrual cramps)
- Migraine headaches
4. How to Use It
Take Froben tablets whole with water, preferably with or after food to reduce stomach irritation. Do not chew or crush the tablets.
- Arthritis: 100 mg two to three times daily (max 300 mg/day)
- Dysmenorrhea: Start with 100 mg at onset, followed by 50–100 mg every 4–6 hours as needed (max 300 mg/day)
Relief may begin in a few days; full effect may take 1–2 weeks.
5. Who Should Use It?
Froben is suitable for adults with:
- Inflammatory joint diseases (e.g., RA, OA, ankylosing spondylitis)
- Soft-tissue injuries (e.g., sprains, tendinitis, bursitis)
- Menstrual pain or dental/post-operative pain
Only take Froben if prescribed by a healthcare professional.
6. Dosage (Overdose and Missed Dose)
- Adults: 200–300 mg/day in divided doses
- Children under 12: Not recommended
Overdose: Seek emergency help. Symptoms include stomach pain, nausea, dizziness, and kidney or liver damage.
Missed dose: Take as soon as remembered. If close to the next dose, skip the missed one—never double the dose.
Off-Label Uses
Some off-label uses include migraine relief and inflammatory eye conditions (e.g., anterior scleritis). These uses should be guided by a doctor.
8. Side Effects Of Froben Tablet
Common:
- Stomach upset, nausea, diarrhea or constipation
- Headache, dizziness
- Fluid retention (swelling), fatigue, indigestion
Rare/Serious:
- GI bleeding or ulcers
- Heart attack or stroke
- Severe allergic reactions (e.g., asthma, hives)
- Liver damage (jaundice, fatigue)
- Kidney injury (low urine output, swelling)
- Skin reactions (e.g., Stevens–Johnson syndrome)
Seek immediate help for severe symptoms.
Drug Interactions
Avoid combining Froben with:
- Blood thinners (e.g., warfarin, aspirin)
- SSRIs or SNRIs (increase bleeding risk)
- Diuretics, ACE inhibitors, ARBs (risk of kidney issues)
- Lithium, methotrexate (increase toxicity)
- Other NSAIDs or corticosteroids
- Alcohol (increases GI risk)
Always inform your doctor about all medications you take.
Warnings and Precautions
Avoid Froben if you have:
- Allergies to NSAIDs or aspirin-sensitive asthma
- Active GI ulcers or bleeding
- Severe kidney, liver, or heart disease
Use with caution if you are elderly, pregnant, or breastfeeding. Do not use in the third trimester. It may impair fertility.
Storage
- Store Froben tablets at 20–25°C in a dry place.
- Keep it away from sunlight.
- Keep out of reach of children and pets.
- Do not use after the expiry date.
Disclaimer
This article is for information purposes only. Please don’t take it as a medical advice.