Insulin glargine is a long-acting insulin. It works slowly and steadily for about 24 hours, so it gives a “background” supply of insulin. Doctors prescribe it for type 1 and type 2 diabetes.
What Is Insulin Glargine Used For?
- Type 1 diabetes, together with mealtime insulin
- Type 2 diabetes, when tablets alone do not control blood sugar
- Keeping blood sugar steady between meals and overnight
How Does Insulin Glargine Work?
Insulin glargine helps your cells take sugar from your blood. After you inject it, it forms tiny crystals under the skin and releases insulin slowly over the day.
General Dosage Information
This is general information only. Your doctor sets the right dose for you, so follow your prescription and the label.
- You inject it under the skin once a day, at the same time each day.
- Your doctor sets the dose based on your blood sugar levels and adjusts it over time.
- Rotate injection sites, such as the belly, thigh, or upper arm. Never share pens or needles.
- Do not mix it or dilute it with other insulins.
Side Effects of Insulin Glargine
Common Side Effects
- Low blood sugar (hypoglycemia): shaking, sweating, hunger, or confusion
- Weight gain
- Redness or swelling at the injection site
Serious Side Effects
Call your doctor or get emergency help if you notice:
- Severe low blood sugar: confusion, seizures, or fainting
- Allergic reaction: rash, swelling, or trouble breathing
- Very low potassium: weakness or irregular heartbeat
Who Should Be Cautious?
- People with kidney or liver disease, who may need lower doses
- People who skip meals, drink alcohol, or exercise a lot
- People who drive, because low blood sugar can be dangerous
Drug Interactions
Tell your doctor and pharmacist about every medicine and supplement you take. Examples of important interactions include:
- Other diabetes medicines: together they can raise the risk of low blood sugar.
- Pioglitazone: it can cause fluid retention and heart failure.
- Beta-blockers: they can hide the warning signs of low blood sugar.
- Corticosteroids: they can raise blood sugar.
- Alcohol: it can cause low blood sugar.
Storage and Precautions
- Keep unopened pens or vials in the fridge between 2°C and 8°C. Do not freeze them.
- Keep the pen you are using at room temperature and use it within 28 days.
- Always carry fast-acting sugar, such as glucose tablets.
Frequently Asked Questions
What should I do if my sugar drops?
Eat or drink 15 grams of fast sugar, such as juice or glucose tablets, and recheck after 15 minutes.
Can I inject it at any time?
Yes, but choose a time and use it at the same time each day.
Can I stop it when my sugar improves?
No. Ask your doctor first.
Disclaimer: This article is for information only. It is not medical advice. Please talk to your doctor about your own health.